（1） Development of separation materials and methods for high performance liquid chromatography and supercritical fluid chromatography.
（2）Applications of separation and purification techniques for pharmaceuticals and natural products.
1. Yu, D. P.; Shen, A. J.; Guo, Z. M.*; Yan, Y. K.; Yan, J. Y.; Jin, G. W.; Liang, X. M.*, A controlled thiol-initiated surface polymerization strategy for the preparation of hydrophilic polymer stationary phases. Chem. Commun. 2015, 51 (79), 14778-14780.
2. Dong, X. F.; Qin, H. Q.; Mao, J. W.; Yu, D. P.; Li, X. L.; Shen, A. J.; Yan, J. Y.; Yu, L.; Guo, Z. M.*; Ye, M. L.*; Zou, H. F.; Liang, X. M.*, In-Depth Analysis of Glycoprotein Sialylation in Serum Using a Dual-Functional Material with Superior Hydrophilicity and Switchable Surface Charge. Anal. Chem. 2017, 89 (7), 3966-3972.
3. Yan, J. Y.; Ding, J. J.; Jin, G. W.; Yu, D. P.; Yu, L.; Lone, Z.; Guo, Z. M.*; Chai, W. G.*; Liang, X. M.*, Profiling of Sialylated Oligosaccharides in Mammalian Milk Using Online Solid Phase Extraction-Hydrophilic Interaction Chromatography Coupled with Negative-Ion Electrospray Mass Spectrometry. Anal. Chem. 2018, 90 (5), 3174-3182.
4. Yan, J. Y.; Ding, J. J.; Jin, G. W.; Duan Z. J.; Yang F.; Li D. D.; Zhou, H.; Li, M.; Guo, Z. M.*; Chai, W. G.*; Liang, X. M.*, Profiling of Human Milk Oligosaccharides for Lewis Epitopes and Secretor Status by Electrostatic Repulsion Hydrophilic Interaction Chromatography Coupled with Negative-Ion Electrospray Tandem Mass Spectrometry, Anal. Chem. 2019, 91(13), 8199-8206.
5. Jin, G. W.; Ding, J. J.; Zhou, Y. Z.; Xia, D. H.; Guo, Z. M.*; Liang, X. M.*, Synthesis and chromatographic evaluation of pyrazinedicarboxylic anhydride bonded stationary phase. J. Chromatogr. A 2021, 1638, 8.
